BSF HCM Previous Year Paper

BSF HCM Previous Year Paper. We covered all the BSF HCM Previous Year Question Paper PDF download in Hindi in this post for free so that you can practice well for the exam.

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BSF HCM Previous Year Objective Paper for Students

Which of the following is a COX-2 inhibitor?

a) Aspirin

b) Ibuprofen

c) Diclofenac sodium

d) Celecoxib

Show Answer

Which of the following adrenergic agonist does not contain a 3, or 4-dihydroxy nucleus?

a) Ephedrine

b) Albuterol

c) Phenylpropanolamine

d) Terbutaline

Show Answer

…….. is a selective ACE inhibitor.

a) Atenolol

b) Ramipril

c) Losartan

d) Nifedipine

Show Answer

Which of the following is third-generation fluoro quinolone?

a) Lomefloxacin

b) Ciprofloxacin

c) Gemifloxacin

d) Gatifoxacin

Show Answer

QSAR stands for.

a) Qualitative structure-activity relationship

b) Quantitative structure action relationship

c) Quantitative structure-activity relationship

d) Qualitative structure activity relativity

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Which of the following is a cholesterol absorption inhibitor?

a) Atorvastatin

b) Ezetimible

c) Fenofibrate

d) Nicotinic acid

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One of the following is HIV NHRT inhibitors.

a) Lopinavir

b) Efavirenz

c) Zidovudine

d) Acyclovir

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Which of the following is not a sulpha drug?

a) Captopril

b) Enalapril

c) Fosinopril

d) Losartan

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Most of the drugs are absorbed in the body by means of.

a) Active transport

b) Passive transport

c) Ion-pair transport

d) Facilitated diffusion

Show Answer

Insulin stimulates glucose transport by promoting the translocation of.

a) GLUT4

b) GLUT 2 and GLUT 4

c) GLUT 1 and GLUT 4

d) GLUT2

Show Answer

Ptyline is secreted by.

a) Pancreas

b) Lachrymal gland

c) Parotid gland

d) None of the above

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The most useful class of drugs in the long-term treatment of hypertension is.

a) Thiazide diuretics

b) Osmotic diuretics

c) Mercurial diuretics

d) Pentazocine

Show Answer

Which of the following drug is not acting on the opioid (Kappa) receptor?

a) Buprenorphine

b) Butorphanol

c) Nalbuphine

d) Pentazocine

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Which of the following crosses the blood-brain barrier?

a) GABA

b) Propranolol

c) Suxamethonium

d) Dopamine

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Select the synonyms of aconite root.

a) Vachang

b) Mouckshood

c) All of the above

d) None of above

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Diosgenin is ……

a) An alkaloid obtained from Dioscorea

b) A carbohydrate from Dioscorea

c) A glycoside from Dioscorea

d) None of above

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Glandula hair having a unicellular or occasionally a short unicellular padiel with a unicellular or bicellular terminal gland is characteristic of.

a) Senna leaves

b) Belladonna Leaves

c) Datura Stramonium leaves

d) Digitalis purpurea leaves

Show Answer

The drug is bacterial to all three pools of extracellular, intracellular, and necrotic caseum of tubercle bacilli.

a) Isoniazide

b) Ethambutol

c) Pyrazinamide

d) Rifampin

Show Answer

Many drugs are chiral. In a synthesis of chiral drug molecules in a symmetric environment.

a) Always one enantiomer is obtained

b) Always both enantiomers are in equal amounts

c) Always both enantiomers are in equal amounts

d) None of the above

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In mammals, the major fat in adipose tissue is.

a) Triglyceride

b) Cholesterol

c) Sphingolipids

d) Phospholipids

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Ferritin is.

a) Coenzyme

b) The stored form of iron

c) Non-protein moiety

d) Isoenzyme

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The active form of Vitamin D in man is.

a) Cholecalciferol

b) Calcifediol

c) Calciferol

d) Calcitriol

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Isotopes differ in.

a) The number of protons

b) The valency number

c) The chemical activity

d) The number of neutrons

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The purity of water for injection is checked by.

a) Potential testing

b) Pyrogen testing

c) Conductivity testing

d) pH Testing

Show Answer

Geometrical isomerism is possible in a case.

a) 2-Pentene

b) Pentane

c) Propene

d) Ethene

Show Answer

Sanguiamarine belongs to the subgroup of.

a) Morphinans

b) Benzyl isoquinolines

c) Phtalide isoquinolines

d) Benzophenathrenes

Show Answer

Dovers powder is used as a diaphoretic contains.

a) Ipecac and Opium

b) Senna and Cinchona

c) Opium and cinchona

d) All of the above

Show Answer

.......... is the dimmer fo flavones and flavonones.

a) Chalcones

b) Aurones

c) Biflavanoids

d) Dihydroflavones

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The wavelength source in the NMR spectrometer is.

a) Goniometer

b) Radiofrequency oscillator

c) High voltage generator

d) Klystron oscillator

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Morphine does not cause.

a) Constriction of the pupil.

b) CNS depression

c) Respiratory depression

d) Diarrhoea

Show Answer

O, M, and P-isomers can be differentiated on the basis of.

a) Chemical Shift

b) Coupling constant

c) Extinction coefficient

d) Dipole moment

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The plasma drug concentration in mcg/ml data obtained after the oral administration of 50mg of a drug are 5.5 in 1h, 9.2 in 2h, 14.9in 3h, 10.3 in 4h, 7.1 in 5 h and 2.2 in 6h. the AUC for the blood data will be.

a) 45.35 mcg/ml.h

b) 55.35 mcg/ml.h

c) 50.35 mcg/ml.h

d) 46.35 mcg/ml.h

Show Answer

Schleuniger tester is used for the tablets to measure

a) Roughness

b) Hardness

c) Dissolution

d) Friability

Show Answer

Creatinine clearance is used as a measurement.

a) Passive renal absorption

b) Glomerular filtration rate

c) Drug metabolism rate

d) Renal excretion rate

Show Answer

Capping in tablets mainly occurs due to.

a) Less upper punch pressure

b) Poor flowability of granules

c) Proper formulation design

d) Entrapment of air in tablet during compression

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The Franz diffusion cell which is used for the evaluation of transdermal drug delivery systems consists of.

a) 1 chamber

b) 2 chambers

c) 3 chambers

d) None of above

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Quick-breaking aerosols are applicable.

a) Orally

b) Parenterally

c) Topical

d) Ophthalmically

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In an osmotic drug delivery system, the drug is released.

a) Polymeric matrix

b) Delivery orifice

c) Plastic matrix

d) None of the these

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The parenteral product must be.

a) Packed-in bottle

b) Sterilized

c) Free from viable

d) living organism

Show Answer

A water attack test is generally performed.

a) USP type I glass

b) USP type II glass

c) USP type III glass

d) All of above

Show Answer

Silicone-based adhesives used in transdermal drug delivery possess.

a) Excellent chemical stability

b) Low toxicity

c) Skin compatibility

d) All of the above

Show Answer

Dose dumping may be a general problem in the formulation of.

a) Soft gelatin capsules

b) Suppositories

c) Modified-release drug products

d) None of the above

Show Answer

Which of the following is useful as a diluent, binder, disintegrating agent as well as a lubricant in tablet formulations?

a) Starch

b) Tragacanth

c) Sucrose

d) None of above

Show Answer

Homatropine is a.

a) Tropine ester of amino acetic acid

b) Tropine ester of mandelic acid

c) Tropine methyl bromide ester of mandelic acid

d) Tropine ester of amino formic acid

Show Answer

A list of the drugs whose import, manufacture and sale, labeling, and packaging are governed by special provisions are included in the schedule.

a) X

b) K

c) H

d) G

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Which of the following radiation has the greatest penetrating powder?

a) Alpha radiation

b) Beta radiation

c) Gamma radiation

d) UV radiation

Show Answer

The energy produced in the UV region produces changes in the.

a) The rotation energy of the molecule

b) The vibrational energy of the molecule

c) The electronic energy of the molecule

d) All of the above

Show Answer

Sanguiamarine belongs to the subgroup of.

a) Morphinans

b) Benzyl isoquinolines

c) Phthalide isoquinolines

d) Benzophenatherenes

Show Answer

Dovers powder is used as a diaphoretic contains.

a) Ipecac and Opium

b) Senna and Cinchona

c) Opium and Cinchona

d) All of above

Show Answer

……….. is the dimmer of flavones and flavonones.

a) Chalcones

b) Aurones

c) Biflavanoids

d) Dihydrofalvones

Show Answer

Isoquinoline alkaloids are biosynthesized via …… pathway.

a) Shikimic acid-tyrosine

b) Shikimic acid-tryptophan

c) Shikimic acid-cathinone

d) None of above

Show Answer

…………. is a precursor for indole alkaloids.

a) Strictosidine

b) Diosgenin

c) Ornithine

d) Hygrine

Show Answer

Catharanthine is an alkaloid of ……. type.

a) Coryname

b) Ibogane

c) Aspidospermane

d) All of above

Show Answer

Different kinds of currents contribute to the polarographic wave.

a) Residual current

b) Migration Current

c) Diffusion current

d) All of the above

Show Answer

The most common causative agent of bacterial pneumonia.

a) Staphylococcus aureus

b) Escherichia coli

c) Sterptococcus pneumonia

d) Mycopalsma pneumonia

Show Answer

Which one of the following devices is useful to increase the efficiency of drug delivery via aerosols?

a) Tube spacer

b) Metered value

c) Actuator

d) Pressure value

Show Answer

Dienosterol is synthesized starting from.

a) p-Hydroxyl acetophenone

b) p-Chloro-propiophenone

c) p-Hydroxy propiophenone

d) p-Chloro acetophenone

Show Answer

Ethacrynic acid belongs to the class of.

a) Loop Diuretic

b) ACE inhibitor

c) Aldosterone antagonist

d) Thiazide derivative

Show Answer

In cephalosporins, the lactam ring is fused with.

a) Thiazolidine system

b) 1,3 dihyrothiazine system

c) Thiazine system

d) Dehydro thiazolidine system

Show Answer

Which of the following is a ß-Lactamse inhibitor?

a) Chloram phenicol

b) Cefadroxil

c) Clavunilic acid

d) Ampicillin

Show Answer

Penicilline on hydrolysis with alkali gives.

a) Penicilloic acid

b) Penaldic acid

c) Penicillic acid

d) Penicillamine

Show Answer

The therapeutic effect of theophylline is achieved at plasma conc. of.

a) 05-15 µg/mL

b) 10-20 µg/mL

c) 15-25 µg/mL

d) 20-30 µg/mL

Show Answer

One of the following antihypertensives has a similar structure as that of the diuretic agent chlorothiazide.

a) Minoxidil

b) Diazoxide

c) Guanethidine

d) Propranolol

Show Answer

Condensation of N-m-hydroxy phenyl 1-N-p-tolyl glycine with ethylene diamine gives.

a) Tolazoline

b) Phentolamine

c) Prazocin

d) Phenoxybenzamine

Show Answer

An important example of liquid-liquid partition chromatography is.

a) Thin layer

b) Column

c) Paper

d) Ion exchange

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In amperometric titrationsm, one of the following is kept constant.

a) Current

b) Resistance

c) Voltage applied

d) Conductance

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In any colorimeter.

a) Unabsorbed radiation is measured

b) Absorbed radiation is measured

c) Absorbed radiation intensity is measured

d) None of above

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Supercritical fluid chromatography is specifically used for the analysis.

a) Thermolabile compounds

b) Thermolabile macromolecules

c) Thermostable macromolecules

d) None of above

Show Answer

An interferone filter consists of.

a) An iron plate coated with selenium

b) A layer of silver on both sides of MgF, deposited on glass

c) A Tungson plate coated with Ago

d) A solid sheet of glass colored by pigment

Show Answer

Tetrabutyl ammonium phosphate is used in HPLC.

a) For adjusting the pH of the mobile phase

b) As stationary phase

c) As a chelating agent

d) As ion pairing agent for anions

Show Answer

Desipramine is metabolized in the liver mainly by. ( bsf hcm previous year paper )

a) N-Oxidation

b) Hydroxylation

c) Both A and B

d) Alkylating agent

Show Answer

2-Amono pyridine and 2-dimethyl amino ethyl chloride are starting materials for the synthesis. ( bsf hcm previous year paper )

a) Mepyramine

b) Diphenhydramine

c) Chlorpheniramine

d) Pheniramine

Show Answer

A 50-year-old male farm worker is brought to the emergency room. He was found confused in the orchard and since then lost consciousness. His heart rate is 45 and his blood pressure is 80/40mmHg. He is sweating and salivating profusesły. Which of the treatment is indicated?

a) Physostigmine

b) Norepinephrine

c) Trimethaphan

d) Atropine

Show Answer

A 45-year-old man who has been injured in a car accident is brought into the emergency room. His blood alcohol level on admission is 275 mg/dL. Hospital records show a prior hospitalization for alcohol-related seizures. His wife confirms that he has been drinking heavily for 3 weeks. What treatment should be provided to the patient if he goes into withdrawal?

a) Pentobarbital

b) Lorazepam

c) Benzodiazepine

d) Phenytoin

Show Answer

The mechanism of action of Ketoconazole is.

a) Inhibits ergosterol synthesis

b) Inhibits DNA gyrase

c) Inhibits dihydropteroate synthetase

d) Induces translation misreadings

Show Answer

Monitoring plasma drug concentration is useful while using. ( bsf hcm previous year paper )

a) Antihypertensive drugs

b) Levodopa

c) Lithium carbonate

d) MAO inhibitors

Show Answer

Phase I oxidative processes frequency involves all of the following, except.

a) Cytochrome P-450

b) NADPH and NADP cofactors

c) Liver endoplasmic reticulum

d) Esterases

Show Answer

All of the following drugs are useful in treating complex partial seizures, except.

a) Ethozuximide

b) Phenobarbital

c) Carbamazepine

d) Phenytoin

Show Answer

Patients suffering from multidrug-resistant tuberculosis can be treated with all of the following drugs.

a) Tobramycin

b) Amikacin

c) Ciprofloxacin

d) Clarithromycin

Show Answer

Which of the following anti-malarial drug is safe during pregnancy?

a) Amodiaquine.

b) Proguanil

c) Primaquine

d) chloroquine

Show Answer

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• BSF Head Constable Ministerial Previous Year Paper
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