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DSSSB Head Clerk Previous Year Paper. We covered all the DSSSB Head Clerk Previous Year Paper in this post for free so that you can practice well for the exam.
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DSSSB Head Clerk Previous Year Objective Paper for Students
In the Liebermann-Burchard test for steroids, the substance is dissolved in
a) Methanol
b) Chloroform
c) Benzene
d) Ethanol
Option b – Chloroform
Rutin is extracted from all of the following plants except
a) Sophora Japonica
b) Fagopyrum esculentum
c) Eucalyptus macrorrhyncha
d) Ginkgo biloba
Option d – Ginkgo biloba
Cinchona robusta is a hybrid of
a) C. Calisaya and C. micrantha
b) C. Succirubra and C. Officinalis
c) C. Calisaya and C. Officinalis
d) C. Calisaya and C. Succirubra
Option b – C. Succirubra and C. Officinalis
The microscopic feature of Eugenia Caryophyllus flower buds includes
a) Collenchymatous parenchyma with many ellipsoidal schizolysigenous oil glands on the outer layer
b) Small transparent endosperm containing aleurone grains
c) Thick starchy cortex with volatile oils in the endosperm
d) Outer layer with rough, dark brown perisperm having reticulate grooves
Option a – Collenchymatous parenchyma with many ellipsoidal schizolysigenous oil glands on the outer layer
The schedule in the Drugs and Cosmetics Act related to disinfectant fluid standards is
a) Schedule – O
b) Schedule – F
c) Schedule – B
d) Schedule – M
Option a – Schedule – O
Single cells in tissue culture can be separated using
a) Mechanical method
b) Filter paper method
c) Enzymatic method
d) Suspension culture
Option b – Filter paper method
The purpose of seal coating during tablet sugar coating is to
a) Prevent moisture from entering the tablet core
b) Shape the edges and increase tablet weight
c) Provide color to the tablet
d) Add shine to the tablet surface
Option a – Prevent moisture from entering the tablet core
Although lactose is a widely used filler in tablet production, it is generally avoided in the formulation of
a) Pyrazinamide
b) Ibuprofen
c) Sulfacetamide
d) Isoniazid
Option d – Isoniazid
One thousand nanograms are equal to
a) Centigram
b) Gram
c) Kilogram
d) Microgram
Option d – Microgram
The aglycone part of steroidal saponins is called “Spirostane” because of its spiro structure at
a) C 22
b) C 19
c) C 13
d) C 18
Option a – C 22
Ephedra sinica and Ephedra equisetina can be differentiated based on their
a) Branching pattern
b) Stomatal features
c) Scaly leaves
d) Alkaloid content
Option c – Scaly leaves
Tetraterpenoids include which of the following
a) Carotenes
b) Xanthophylls
c) Carotenoidic acid
d) All of the above
Option d – All of the above
Vincristine and Vinblastine perform their action by
a) Disrupting t-RNA synthesis
b) Preventing DNA fragmentation
c) Binding to proteins
d) Interfering with folic acid pathways
Option c – Binding to proteins
The lycopodium spore method helps determine the purity of crude drugs that contain
a) Multi-layered cell structures
b) Countable distinct particles
c) Oil globules
d) Particles with irregular thickness but measurable length
Option b – Countable distinct particles
Creatinine clearance is commonly used to assess
a) Glomerular filtration rate
b) Renal excretion rate
c) Drug metabolism rate
d) Passive renal excretion
Option a – Glomerular filtration rate
The primary bacteria responsible for bacterial pneumonia is
a) Bacillus stearothermophilus
b) Bacillus subtilis spores
c) Streptococcus pneumoniae
d) Mycoplasma pneumonia
Option c – Streptococcus pneumoniae
Riboflavin is metabolically active in the form of
a) FMN and FAD
b) NADP and NADPH
c) AMP and ATP
d) Retin and Retinine
Option a – FMN and FAD
Bacteria that obtain both nutrients and energy from inorganic sources are called
a) Autotrophs
b) Heterotrophs
c) Parasites
d) Saprophytes
Option a – Autotrophs
Which vitamin is used in the treatment of scurvy
a) Vitamin A
b) Vitamin D
c) Vitamin C
d) Vitamin E
Option c – Vitamin C
Yeast is considered a rich source of
a) Vitamin A
b) Vitamin B
c) Vitamin C
d) Vitamin D
Option b – Vitamin B
The BCG vaccine should be administered at
a) Birth
b) 6 months
c) 1 year
d) 2 years
Option a – Birth
For maintaining strong bones, which vitamin is recommended
a) Vitamin A
b) Vitamin D
c) Vitamin C
d) Vitamin E
Option b – Vitamin D
Which enzyme is known as a spreading factor
a) Heparin
b) Chondroitin
c) Hyaluronidase
d) Iduronic acid
Option c – Hyaluronidase
Antigenic preparations made from bacterial exotoxins are called
a) Vaccines
b) Toxoids
c) Endotoxins
d) Sera
Option b – Toxoids
The vitamin known as the anti-sterility vitamin is
a) Vitamin K
b) Vitamin D
c) Vitamin E
d) Vitamin A
Option c – Vitamin E
The richest dietary source of lecithin is
a) Meat
b) Fish
c) Chicken
d) Egg yolk
Option d – Egg yolk
Passive immunity is achieved by introducing
a) Antiserum
b) Antigens
c) Vaccines
d) Antibodies
Option d – Antibodies
Which acid is a component of bacterial cell walls
a) Muranic acid
b) Formic acid
c) Stearic acid
d) Palmitic acid
Option a – Muranic acid
Preparations containing weakened or killed viruses are known as
a) Vaccines
b) Antiserum
c) Toxins
d) Toxoids
Option a – Vaccines
Yeasts are classified under
a) Bacteria
b) Fungi
c) Protozoa
d) Viruses
Option b – Fungi
Sterols are categorized as
a) Lipids
b) Waxes
c) Carbohydrates
d) Proteins
Option a – Lipids
A hypotonic solution can be made isotonic by adding
a) Sodium chloride
b) Potassium chloride
c) Calcium chloride
d) Magnesium chloride
Option a – Sodium chloride
Tuberculosis is commonly identified using
a) Widal test
b) ELISA test
c) Mantoux test
d) Alerts method
Option c – Mantoux test
Rod-shaped bacteria are known as
a) Coccus
b) Spirilla
c) Bacillus
d) Vibrio
Option c – Bacillus
The Widal test is performed to detect
a) Typhoid
b) AIDS
c) Jaundice
d) Meningitis
Option a – Typhoid
Entamoeba histolytica causes which of the following diseases
a) Malaria
b) Trypanosomiasis
c) Filariasis
d) Amoebiasis
Option d – Amoebiasis
The condition where harmful bacteria are present in the bloodstream is called
a) Toxemia
b) Septicemia
c) Bacteremia
d) Anemia
Option b – Septicemia
Dettol is commonly used as a
a) Antiseptic
b) Disinfectant
c) Antimicrobial agent
d) Anemia treatment
Option a – Antiseptic
The mesh size in the Indian Pharmacopoeia disintegration apparatus is
a) 2.00 mm
b) 4.00 mm
c) 3.00 mm
d) 1.50 mm
Option a – 2.00 mm
Which of these mills operates using both attrition and impact principles
a) Cutter mill
b) Hammer mill
c) Roller mill
Select the appropriate excipient used to improve tablet solubility
a) PEG
b) Microcrystalline cellulose
c) Talc
d) Lactose
Option a – PEG
The area under a drug’s serum concentration-time curve indicates
a) The drug’s half-life
b) The initial dose of the drug
c) The total amount of drug absorbed
d) The amount of drug excreted in urine
Option c – The total amount of drug absorbed
‘Unna Paste’ composition includes
a) Zinc oxide
b) Zinc oxide and Sulfur
c) Zinc oxide and Gelatin
d) Zinc oxide and Boric acid
Option d – Zinc oxide and Boric acid
Capping of tablets is mainly caused by
a) Trapped air
b) Excessive moisture
c) Rapid evaporation
d) None of these
Option a – Trapped air
In aerosol containers, the dip tube is typically made from
a) Polypropylene
b) Glass
c) Stainless steel
d) Aluminium
Option a – Polypropylene
In the intestinal lining, retinal is converted to retinol using which coenzyme
a) NADPH + H+
b) FAD
c) NAD
d) NADH + H+
Option d – NADH + H+
The international standard for Vitamin A is based on the activity of
a) 0.3 µg of Vitamin A alcohol
b) 0.344 µg of Vitamin A alcohol
c) 0.6 µg of Vitamin A alcohol
d) Micrograms of Vitamin A alcohol
Option d – Micrograms of Vitamin A alcohol
Substances that share the same molecular structure but differ in spatial arrangement are called
a) Epimers
b) Anomers
c) Optical isomers
d) Stereoisomers
Option d – Stereoisomers
In the bloodstream, retinol is transported attached to
a) Aporetinol-binding protein
b) Beta-globulin
c) Gamma-globulin
d) Albumin
Option a – Aporetinol-binding protein
Among these options, the most irritating solution to the eyes is
a) Purified water
b) 0.7% sodium chloride solution
c) 0.9% sodium chloride solution
d) 1% sodium chloride solution
Option a – Purified water
Carotene, a Vitamin A precursor, is broken down by
a) Carotene dioxygenase
b) Oxygenase
c) Hydroxylase
d) Transferase
Option a – Carotene dioxygenase
Fat-soluble vitamins generally have which of the following characteristics
a) Soluble in alcohol
b) Contain propane units
c) Are stored in the liver
d) All of these
Option d – All of these
The primary sources of preformed Vitamin A are
a) Milk, fats, and liver
b) Yellow vegetables
c) Yellow fruits
d) Leafy green vegetables
Option a – Milk, fats, and liver
The interconversion of Retinol and Retinal depends on enzymes working with
a) NAD or NADP
b) NADPH
c) FAD
d) NADH + H+
Option d – NADH + H+
Testing and verification of VDRL antigens is the responsibility of
b) Excise commissioner
c) Serologist and chemical examiner
d) Drug controller of India
Option d – Drug controller of India
Chloramphenicol is classified under which schedule
a) G
b) H
c) W
d) P
Option b – H
Glycerose is an example of which type of sugar
a) Aldose
b) Ribulose
c) Erythrulose
d) Dihydroxyacetone
Option a – Aldose
Which of the following is a triose sugar
a) Glycerose
b) Ribulose
c) Erythrulose
d) Fructose
Option a – Glycerose
Ribulose is categorized as which type of sugar
a) Dihydroxyacetone
b) Pentose
c) Erythrulose
d) Glucose
Option b – Pentose
As per the Drugs and Cosmetics Act, Schedule D refers to
a) Drugs excluded from import regulations
b) Conditions that drugs cannot claim to prevent or cure
c) Factory premises requirements
d) List of prescription medications
Option a – Drugs excluded from import regulations
Who is an Ex-Officio member of the State Pharmacy Council
a) Chief pharmacist of a government hospital
b) Chief administrative medical officer of the state
c) Registered pharmacist
d) Assistant drug controller
Option b – Chief administrative medical officer of the state
Who issues the Education Regulations in the official gazette ( DSSSB Head Clerk Previous Year Paper )
a) Ministry of Education
b) Central Government
c) Drug Controller
d) President of the Pharmacy Council of India
Option b – Central Government
According to Schedule M of the Drugs and Cosmetics Act, the minimum area for manufacturing cosmetic aerosols is
a) 15 m²
b) 25 m²
c) 30 m²
d) 35 m²
Option c – 30 m²
How many elected members should be present in a State Pharmacy Council
a) Six
b) Nine
c) Five
d) Seven
Option a – Six
Schedule Y in the Drugs and Cosmetics Act covers ( DSSSB Head Clerk Previous Year Paper )
a) Disinfectant standards
b) Manufacturing premises requirements
c) Clinical trials, import, and new drug production
d) Standards for surgical dressings
Option d – Standards for surgical dressings
The organism used to test ampicillin in microbiological assays is
a) Micrococcus luteus
b) Staphylococcus aureus
c) Bacillus subtilis
d) E. coli
Option c – Bacillus subtilis
Staphylococcus aureus produces which pigment during growth
a) Red
b) Green
c) Yellow
d) Black
Option a – Red
In suspensions, the solid particles typically have a size greater than
a) 0.5 µm
b) 0.4 µm
c) 0.2 µm
d) 0.1 µm
Option a – 0.5 µm
HPMC is used in matrix tablets as a ( DSSSB Head Clerk Previous Year Paper )
a) Hydrophilic matrix-forming agent
b) Enteric coating material
c) Plastic component
d) Wax coating agent
Option a – Hydrophilic matrix-forming agent
Particle size in pharmaceutical aerosols can be measured using
a) Cascade Impactor and Light Scatter Decay
b) Light Scatter Decay and Karl Fischer Method
c) Karl Fischer Method and IR Spectroscopy
d) Cascade Impactor and IR Spectroscopy
Option a – Cascade Impactor and Light Scatter Decay
To prepare a 12% ointment, how many parts of 10% ointment should be mixed with 2 parts of 15% ointment ( DSSSB Head Clerk Previous Year Paper )
a) 2
b) 3
c) 5
d) 6
Option b – 3
Which drug is converted into a cytotoxic compound during metabolism
a) Vincristine
b) Dactinomycin
c) 5-Fluorouracil
d) Lomustine
Option c – 5-Fluorouracil
Which drug shows cell-specific cytotoxic activity ( DSSSB Head Clerk Previous Year Paper )
a) Methotrexate
b) Dactinomycin
c) Cisplatin
d) Mechlorethamine
Option a – Methotrexate
Which antiviral drug has the highest selectivity for viruses over human cells
a) Interferon
b) Amantadine
c) Acyclovir
d) Zidovudine
Option c – Acyclovir
Aspirin should be avoided in patients with ( DSSSB Head Clerk Previous Year Paper )
a) Muscle pain
b) Fever
c) Peptic ulcers
d) Rheumatoid arthritis
Option c – Peptic ulcers
A water-soluble coating material used in microencapsulation is
a) Polyethylene
b) Silicone
c) Hydroxyethylcellulose
d) Paraffin
Option c – Hydroxyethylcellulose
The Keller-Kiliani test is used to detect ( DSSSB Head Clerk Previous Year Paper )
a) Digitalis
b) Clove
c) Fennel
d) Senna
Option a – Digitalis
Who is known as the “Father of Medicine”
a) Paracelsus
b) Aristotle
c) Galen
d) Hippocrates
Option d – Hippocrates
Ruthenium red is a reagent used to identify
a) Gums
b) Lipids
c) Waxes
d) Mucilage
Option a – Gums
Isapgol seeds are primarily used as a ( DSSSB Head Clerk Previous Year Paper )
a) Laxative
b) Purgative
c) Cathartic
d) Digestive agent
Option a – Laxative
Which of the following is not obtained from dried latex
a) Opium
b) Gutta-percha
c) Papain
d) Balsam
Option d – Balsam
Soxhlet apparatus is commonly used for ( DSSSB Head Clerk Previous Year Paper )
a) Filtration
b) Clarification
c) Extraction
d) Size reduction
Option c – Extraction
The primary medicinal use of Digitalis is as a
a) Heart stimulant
b) Pain reliever
c) CNS stimulant
d) Laxative
Option a – Heart stimulant
Coriander mainly contains
a) L-borneol
b) Pinene
c) D-linalool
d) Geraniol
Option c – D-linalool
Borntrager’s test helps to detect the presence of ( DSSSB Head Clerk Previous Year Paper )
a) Coumarins
b) Saponins
c) Anthraquinones
d) Steroids
Option c – Anthraquinones
Vinca is a natural source for drugs used as
a) Antitumor agents
b) Cough suppressants
c) Diuretics
d) Antimalarial drugs
Option a – Antitumor agents
Silicone oils used in topical formulations are classified as
a) Natural oils
b) Semi-synthetic oils
c) Polymers
d) Animal oils
Option c – Polymers
Glycoalkaloids are compounds that ( DSSSB Head Clerk Previous Year Paper )
a) Contain sulfur along with nitrogen
b) Are glycosidic in structure
c) Break down to release alkaloids
d) Always contain cyclic sulfur
Option b – Are glycosidic in structure
Which statement correctly describes Ginseng root
a) It is one of the most exported plants from Brazil
b) It is derived from Panax ginseng and Panax quinquefolium
c) It is collected from plants less than one year old
d) It contains quinindiol derivatives
Option b – It is derived from Panax ginseng and Panax quinquefolium
Hashish is a drug obtained from the flowers of which plant ( DSSSB Head Clerk Previous Year Paper )
a) Neem
b) Hemp
c) Rose
d) Tulsi
Option b – Hemp
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